Welcome to the
Division of Orthopaedics

Orthopaedics at the U of T has a long tradition of developing innovative treatment approaches, performing research of the highest quality, developing new education programs, and providing clinical care of the highest quality possible. We are leaders in the field, and our faculty members play leadership roles nationally, and internationally. Read more »

Division Chairs for Orthopaedics - University of Toronto Orthopaedic Chairs 1976 - Today.
From left to right - Ben Alman (2006-Today), James Waddell (1996-2006), Robert Salter (1976-1986), Allan Gross (1986-1996).

Ferguson, Dr. Peter

Peter Ferguson

Mount Sinai Hospital
600 University Avenue, Suite 476(G)
Toronto, ON
M5G 1X5
Tel: 416 586-4800 x8687
Fax: 416 586-8397
Email: pferguson@mtsinai.on.ca

Specialty Interest:
Orthopaedic Oncology

Sherry Leal, Secretary
Tel: 416 586-4800 x8687
Email: shleal@mtsinai.on.ca

Basic Research Activity

Tissue engineering techniques to enhance impaired wound healing. We have observed that patients who undergo radiation prior to surgical excision of sarcomas in the extremities have a high incidence of wound healing complications. Our focus is on elucidating the mechanisms whereby radiation impairs wound healing and also to examine various interventions to overcome this deficit. Currently we are exploring two areas: cell therapy, using bone marrow stromal cells that can differentiate into wound healing fibroblasts; and use of synthetic materials to act as wound fillers and that can harbour cell growth prior to implantation.

Biomechanical modeling of metastatic lesions in long bones. Metastases are the most common neoplasia presenting in the skeleton and cause significant disability and morbidity. We have an interest in finite element modeling of metastatic lesions in the femur and humerus to determine lesions that are at greatest risk of pathologic fracture. Furthermore, we wish to examine different types of fixation of metastatic lesions using finite element analysis and cadaver biomechanical testing.



Clinical Research Interests
Orthopaedic Oncology

Selected Publications

Ferguson PC, Boynton EL, Wunder JS et al. Intradermal injection of autologous dermal fibroblasts improves wound healing in irradiated skin. J Surg Res 1999;85:331-338.

Dantzer D, Ferguson P, Hill RP et al. Effect of radiation and cell implantation on wound healing in a rat model. J Surg Oncol 2003;83:185-190

Publications:
www.ncbi.nlm.nih.gov/PubMed/